The National Cancer Institute states that the purpose of most listed clinical trials is to test new cancer treatments or new methods of diagnosing, screening for or preventing cancer. Because all potentially harmful side effects are not known before a trial is conducted, dose and schedule modifications may be required for participants if they develop side effects from the treatment or test. The therapy or test described in each clinical trial is intended for use by clinical oncologists in carefully structured settings, and may not prove to be more effective than standard treatment. A responsible investigator associated with this clinical trial should be consulted before using this protocol.
At present, the following trials are actively testing new drugs or treatments for mesothelioma. They are listed by title with a short description and have no particular order or endorsement.
- Phase II Pilot Study of Cyclophosphamide and Active Intralymphatic Immunotherapy With a Vaccine Containing Interferon alfa or Interferon gamma-Treated Tumor Cells Followed By Sargramostin (GM-CSF) in Patients With Advanced Cancer
Click here for an abstract of this trial
- Phase II Pilot Study of Surgery and Adjuvant Intracavitary Photodynamic Therapy With Large Diffuser Fibers in Patients With Malignant Mesothelioma
Click here for an abstract of this trial
- Phase II Study of Neoadjuvant Pemetrexed Disodium and Cisplatin Followed By Extrapleural Pneumonectomy and Radiotherapy in Patients With Stage I, II, or III Pleural Mesothelioma
Click here for an abstract of this trial
- Phase II Randomized Study of Pemetrexed Disodium Combined With Either Gemcitabine or Carboplatin in Patients With Advanced Malignant Mesothelioma of the Pleura
Click here for an abstract of this trial
- Phase II Study of AZD2171 in Patients With Unresectable Malignant Pleural Mesothelioma
Click here for an abstract of this trial
- Phase II Study of Bevacizumab (Avastin) and Erlotinib (Tarceva) in Previously Treated Mesothelioma
Click here for an abstract of this trial
- Phase II Study of Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate
Click here for an abstract of this trial
- Phase II Study of AZD2171 in Patients With Malignant Pleural, Peritoneal, or Tunica Vaginalis Mesothelioma That is Not Amenable to Curative Surgery
Click here for an abstract of this trial
- Phase II Study of Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma
Click here for an abstract of this trial
- Phase II Study of Induction Combination Chemotherapy Comprising Methotrexate, Vinorelbine Ditartrate, and Cisplatin With or Without Surgery and Adjuvant Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma
Click here for an abstract of this trial
- Phase II Study of PDX101 as Second-Line Therapy in Patients With Unresectable Malignant Pleural Mesothelioma
Click here for an abstract of this trial
- Phase I/II Study of PTK787 and Pemetrexed With or Without Cisplatin for Lung Cancer
Click here for an abstract of this trial
- Phase I Study of Cisplatin, Imatinib Mesylate, and Pemetrexed in Malignant Mesothelioma Patients
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- Phase I Study of Decitabine and FR901228 (Depsipeptide) in Patients With Unresectable Pulmonary, Esophageal, or Pleural Malignancies
Click here for an abstract of this trial
- Phase I Study of Flavopiridol in Patients With Metastatic or Unresectable Refractory Solid Tumors or Hematologic Malignancies
Click here for an abstract of this trial
- Phase I Study of FR901228 (Depsipeptide) and Flavopiridol in Patients With Advanced Lung or Esophageal Cancer, Malignant Pleural Mesothelioma, or Lung or Pleural Metastases
Click here for an abstract of this trial
- Phase I Study of Suberoylanilide Hydroxamic Acid in Advanced Solid Tumors
Click here for an abstract of this trial
- Phase I Study of Cetuximab in Combination With Tarceva in Patients With Solid Tumors
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- Phase I Study of Gene Therapy for Pleural Malignancies
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- Phase I Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer
Click here for an abstract of this trial
- Phase I Study of BMS-275183 (Oral Taxane) Given on a Daily Schedule in Combination With Esomeprazole (Nexium) in Patients With Advanced Cancer
Click here for an abstract of this trial
- Phase I Pilot Study of Wilms Tumor-1 Analog Peptide Vaccine and Sargramostim (GM-CSF) in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma
Click here for an abstract of this trial
Diagnostic Trials
Multiple Biomarkers in Undiagnosed Pleural Effusion
Click here for an abstract of this trial
Study of the Etanidazole Derivative EF5 for the Detection of Hypoxia and Vascularity in Patients With Intraperitoneal or Pleural Malignancies Treated With Photodynamic Therapy
Click here for an abstract of this trial |
